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Question:

Which of the following is NOT a function of the kidneys?

     A. Produce active vitamin D
     B. Synthesize renin
     C. Synthesize albumin
     D. Excrete drugs
     E. Synthesize erythropoietin
 
Answer:

  1. The kidney regulates fluid and electrolyte balance by filtration, secretion and reabsorption.

  2. The kidney is an endocrine organ - it activates both erythropoeitin (for production of red blood cells) and vitamin-D (which regulates calcium metabolism).

  3. It also produces renin (in the afferent arteriole) which affects various aspects of water and electrolyte homeostasis.

  4. Regulates acid and base balance. The nephron secretes both hydrogen and bicarbonate ions into the tubles and prevents reabsorption of Hydrogen ions and bicarbonate ions to decrease accumulation acids and bases in the extracellular compartment.

  5. Facilitates excretion of metabolic waste and products and foreign bodies.

  6. Glucose synthesis from amino acids occurs in the kidney during prolonged fasting.

  7. Regulation of arterial pressure by production of vasoactive factors such as renin that leads to release of angiotensin.

Therefore, kidneys DO NOT synthesize albumin. The answer is C.

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